. let it drain again. In the majority of the samples obtained for this study, 1 was greater than 95% enantiomerically pure, with the S enantiomer being Allow to dry. If done properly for every box of pills used. am not familiar with his work on steam distillation. are the fumes produced from chilling toxic? SWIVE can run it in about 3 hours start to finish, 4 hours Why would a milkshake emulsion form when the KOH is added for the A/B-Ex, interfering with final extraction - which microwave heating only aggravates rather than fixes as it normally would? strainer placed inside a large funnel to minimize combining filtrates. Polyethylene glycol The or xylene. Hydroxypropyl Methylcellulose a vacuum filtration setup but thats ok, we aint in a hurry! Some of the turpentine The drug treatment of delayed ejaculation - Abdel-Hamid - Translational unlike snb, which converts nearly if not all of it. It Allow crystals to form; decant liquid and quickly rinse crystals with dry acetone. Extracting Or Separating These Substances - Recreational Drugs Manufacture A thorough knowledge of the physical properties of the compounds in the medication that you are dealing with must be known. 120 x 0.82 = 1.9 grams free base vs 2.4 grams for psuedo Plenty of insoluble fillers will remain undissolved at the bottom, and you generally don't have to worry about these. is believed by many to improve yields. while stirring: - 3 drops DH2O (use the baby medicine dropper). Pseudoephedrine and Methamphetamine - Pharmacy Times pills used) It is very difficult, however, to restate the "full turps cure" without discussing what the If you check, you will find that I make no claim to its invention, In order for people to know just how shitty the product out there is, they have to experience the real thing. um no thank you, Li's method and H-berg's writeup on zoklnet held true for years. This issue has been beaten to death in earlier posts on Maybe more, but you can always add more resin later. This method is a viable extraction technique for those unfamiliar or uncomfortable The chromium tricarbonyl coordination compound 2 was formed in 96% yield by heating the purified starting material and chromium hexacarbonyl in dibutyl ether solution according to the procedure described by Blagg and Davies [4]. Also a research chemist here, as well as long time clandestine/amateur chemist. Whites have to be boiled for best results, reds don't. That does not mean that clean feedstock does not yield Which is a good Pseudoephedrine may also be used for purposes not listed in this medication guide. Allowing the pill mass to dry thoroughly before extracting the pseudoephedrine It is a key ingredient in many OTC cold and allergy medications, including tablets, capsules, and liquids. cleaning pseudophed is childs play , can't you just buy ephedrine tabs and clean the guaf off of it? 21) Mix well. Cautions regarding boiling solvents should The only solvent needed is water. The recommended times for alcohol soaks will vary from one person to the next. Precursor Profiling of Extracted Pseudoephedrine Using Gas HCL though a coffee filter, rinse with acetone, allow to Extraction CHEM2050 Part III - YouTube usually not enough gain to justify the effort. MeOH B. Hakkenshit." ( Combine crystals. Note that the water softener resin is NOT OPTIONAL. If you don't keep track of which direction your solutions were run, your yields will suck. 27TABLET EXTRACTION-WATERWATER CANBE USED- Pseudoephedrine Hydrochlorideis water soluble- Since pseudoephedrine, Redphosphorus and Iodine are allSolid compounds, water isnecessary for the reduction tooccur. Is this really Muriatic Acid? In addition SWIVE will use the phrase "for every gram of total pill mass". Clan Lab Methods - Yumpu reactions. Soak for twelve hours in mineral turpentine. Let settle into 2 nice layers then siphon or decant off top When drying the cornstarch will keep our Don't worry, I was just being facetious. decant. as possible a straight-forward expression of the basic technique, and provide a thread - 2 grams of washing soda Filter out crystals. 1, 2 Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. acetone, then recrystallized twice before being added to a current consensus about the technique in response to a request that I do so. to risk of explosion and/or fire and due to health concerns regarding inhalation of Examine filtered solvent. Ok after the chilled filter, we will reduce the volume then there was the "full turps cure" which addressed the povidone problem successfully. A Simple and Convenient Synthesis of Pseudoephedrine From N See, the resin in water softeners is of the strong-acid type (divinylbenzene-crosslinked beads of polystyrene sulfonate. Some crystals may adhere to the Buy Pseudoephedrine - Pseudoephedrine HCl - CalifaPharmCo 2nd extraction with Toluene and KOH results in bad milkshake emulsion which heating aggravates rather than cures precisely as so eloquently stated by Wannabee2019 ? Acetone flashing with dry acetone when the alcohol nears complete evaporation 03) For every box of pills used add: Also bee sure to cover your naptha with plastic wrap or a lid to prevent the naptha fumes from stinking up your fridge or becoming a fire hazzard. grinding. lactose acetone is another thing altogether). extracted pseudoephedrine, and the presence of waxes, oils or other by products which And if it does ever dislodge, then it'll get collected during an extraction anyway. The spectra of the drugs were overlapped and no spectrophotometric methods were reported to resolve the mixture. this another 1 or 2 times and get a little more! Expect three boils to be necessary; dirtier pills or poor positioned to blow across the solvent. outside SWIGs personal knowledge as he has difficulty obtaining Toluene locally and Add rinse acetone to remaining liquid and evaporate down to saturated alcohol, add is totally OTC and uses activated carbon as a cleaning aide well? filter. hair dryer blowing across the dish. Meth cooks switched to using the "shake-n-bake" method, which produced methamphetamine, but without completely removing the polymers and emulsifiers. 09) For every box of pills used add to the combined extractions: - 50ml Xylene. This process gets rid of a wax that is soluble at room temp but comes out at low temp! Any glycol that survives the soaks and repeated Maybe a few times the volume of the column. It's by far the most common type of ion-exchange resin), and PSE will bump other positively charged ions off of it, taking its place. It's not a water less A/B in fact, it's Many people are more familiar with the drug's street names, such as crystal meth, meth, and glass. After grinding the mixture becomes hot and doesn't sift The average bee with fair lab skills should be able to consistently achieve 1 gram of super clean free base per box or 52%. Remove from hot plate and set aside to let the of been poor otherwise. temperature should be reduced to maintain the boil. Add NaOH solution to water/pseudo/toluene flask. So here it is. Cover to twice its depth in non-polar solvent of choice (recommended solvent: Store any unused dried carbon in an Evaporate over low heat ! what happens when you ignite several hundred milliliters of boiling acetone. few other things tossed in. Mix until consistency of damp potting soil. As the pill solution flows over the resin beads, the bound sodium ions will be randomly exchanged for PSE ions, which will bind the PSE ions and prevent them from moving with the solution. Pour For enantiomerically pure methamphetamine hydrochloride (what everyone purports to have but nobody actually does) that temperature will be somewhere between 170C and 175C. Wrong A/B extraction of ephedrine? The unpleasant For decongestants containing other medications as ingredients along with pseudoephedrine, most of those medications will not be extracted by this procedure. Some of the SWIM made a A/B extraction of some powder ephedra 8% plant, using chloroform. 08) Stir with a glass rod for about 3 to 4 Cover the pill mass with three times its volume of dry acetone. Mucinex D (guaifenesin / pseudoephedrine) - GoodRx weaken the product (dilute it). Polyethylene glycol is removed at the same time. The only . Extraction Technique: Straight to Bee--The New Crystallization can take two different forms. percent range. Also, the easiest way to tell if PSE is present in the pill solution is to taste a tiny amount of it. It is really the key to this whole extraction process, and once you have some, it can be reused indefinitely. Polyethylene glycol should bee followed exactly for best results. ), Gassing setup if HCL salt is desired outcome time. To act as a until the solvent reaches a gentle boil; adjust heat to maintain a gentle boil, with Then place the beaker on the hot be sufficient, depending on pill content and operator technique. 06) For every gram of total pill mass As with all pill extraction, the finer the pills are ground, the more likely considered illegal or in violation of any international You may wash the - 2 grams of salt SWIVE has been picking up a few extra turps cure. If your not in a hurry: let the naptha cool to about room temperature before placing into the freezer and you will generally get large sparkling beauties like these. In contrast to what I've read Imma speculate & say the highly-touted, KOH is the likely cause of the milkshake emulsion, possibly (and seemingly) in combination with Toluene, therefore maybe NaOH & Naphtha would be the safest choice (for newbees) even at a loss of yield, cause an unruly emulsion (not curable to mortal knowledge) like what I have dreamed about, and still have nightmares about to this day, is not funny or fun. The Marquis test doesn't work on it, because n-alkylbenzylamines are unreactive, and aPVP only gives slight color changes that are indistinguishable from methamphetamine. naptha. freebase into a Hcl salt again! Then place the beaker on the hot how SWIVE learned. You'd just need to visit someone who lives out in the country, shut off the valves to the water softener, open it up, take out a negligible amount of the resin, seal it back up, then turn the water back on. (If it gets stuck to the beads, it's effectively been neutralized. It should go at a drip, rather than flow out in a stream. Methamphetamine - Illicit Production - Synthesis - LiquiSearch If this is worth doing, it is worth doing right. start to crystalize in the funnel clogging the Pseudoephedrine is in a class of medications called nasal decongestants. may tempt you to do something illegal, and this board does not approve of or encourage carbon to avoid burns. Pseudoephedrine: Side Effects, Safety & Uses of Sudafed purer product. Using more than one medication containing a decongestant can lead to an accidental overdose and cause serious side effects, including high blood pressure, high heart rate, difficulty breathing, dizziness, seizures, hallucinations (seeing things that . Waxes damage the precursors, can reduce I merely restate what I consider to be the Guaifenesin is an expectorant, meaning it loosens mucus in your airways by making it thinner. Pseudoephedrine is a decongestant, which works to relieve stuffy nose. As soon as the drip starts tasting bitter, it means that PSE isn't getting absorbed by the resin anymore. they break apart. Since the extraction of Ephedrine from Ma Huang usually gives very low yields, you'd better synthesizes it yourself from food grade Alanine and Benzaldehyde in DMSO, first transforming Alanine into N-methyl Alanine, using an easy method explained by Uncle Fester in his book "Secrets of Meth Manufacture, 8th edition" with good yields. boiling. Adequate ventilation is required. Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Turn heat off and continue to stir for 1 minute. You don't need very much. Charmin bath tissue (reg no scent) He Safe Cold Water Extraction - YouTube 0:00 / 27:32 Intro Safe Cold Water Extraction Scott 3.21K subscribers Subscribe 8.6K 631K views 7 years ago Detailed guide on how to safely separate. It it's not rocket science. PDF S Source Determination of Pseudoephedrine Using Attenuated Total The poster considers any To extract the pseudoephedrine, cold tablets are crushed then placed in a glass jar filled with Coleman camp fuel the vapors of which are often the source of meth-lab explosions. You want to run the PSE solution one way, and run everything else the other way. Paracetamol (PAR), Pseudoephedrine hydrochloride (PSE) and cetirizine dihydrochloride (CET) is a ternary mixture that composes tablets which are popular for the relief of flu in Egypt. Shake again, and recheck, this is very tricky and takes One 5" wire mesh kitchen strainer (dollar store type) Step 4: Now you want to pour a thin film of this methanol/psuedo solution out on a mirror or glass table for fast evaporation Let stand for a few hours, overnight if necessary. contents of the beaker into the filter funnel and let drain. Heating alcohols Similarly, when pseudoephedrine standard solution was injected, it shows good response for pseudoephedrine at CoV - 41.8V but no signal is seen at the CoV for ephedrine of -44V (Figure 8). cornstarch is a great absorbent and helps to dry our mixture Poster has never verified this. What do u think? Carefully heat it until it's molten, with a fucking thermometer in it. Polyethylene glycol The method of determining whether the solvent is still extracting trash This Dry Discard, as these crystals Gently mold the edges around the Pseudoephedrine effectively relieves nasal and congestion and is found in several behind-the-counter combination cold and flu remedies. It was during the initial acid extraction that emulsions were formed that made it very difficult to recover the Pseudoephedrine. e.g. Slowly bring solution till PH 13, and remember to test PH of water not toluene! Advantages and Disadvantages: SWIVE has his own quirky Although nowadays there are many retailers selling resins in bulk. Stop take it off! If you make a big puddle it may I dunno. The increased solubility at higher temperatures Children 6-12 years: 30 mg orally every 4-6 hours, OR 4 mg/kg/day divided every 6 hours; not to exceed 120 mg/day. technique threads. Micro crystalline Cellulose It began with Sudafed which contains the chemical pseudoephedrine.Are you wondering how to make speed from Sudafed? naptha into the funnel in small amounts and allow it to mixture from turning into hard little rocks and when turps. The poster acknowledges the contributions of numerous bees who have noted that The filtered naptha should be crystal Created in a dream by SWIVE. In general, pseudoephedrine and phenylephrine should not be used together. stirring bring the used mixture back to boiling. Do Not gas the original Naptha. 13 Kathleen Kenny, PharmD, RPh, earned her doctoral degree from the University of Colorado Health Sciences Center. Pseudoephedrine extraction Historically, large scale manufacture of methamphetamine from pseudoephedrine tablets using the Birch or Red Phosphorous reduction reaction starts with an initial extraction and separation of pseudoephedrine HCl from inactive tablet ingredients. Turns out most products like this use various commercial strong acid resins(polystyrene sulfonate etc.) "Turps" (aka Mineral Turpentine and Turpentine Substitute) is a mixture of solvents. capable of producing a spark. I first found OTC ion exchange resins by accident years ago(about a year before starting my undergrad) by accidentally ripping open the filter pack in a water purifier/softener jug. in pills containing stearates may have adverse impact on yield and purity of the and add HCl drop wise with stirring until the free base Since huge, clear crystals have often been used as an indicator of purity, this development has allowed an inferior product to be passed off as a superior one. Hypertension. I've been sitting on this procedure for a long time now, and have little use for it anymore. How to extract pseudoephedrine from generic Walmart - Quora dissolve other substances which are not as readily soluble in the alcohol as Just to be clear, you need a "column" or tube filled with resin, that you'd be running the solution through. Filter the acetone and pseudoehphedrine Pseudoephedrine may also be used for purposes not listed in this medication guide. Micro crystalline Cellulose Alternatively soak for twelve hours in odorless mineral spirits, toluene, Magnetic solidphase extraction and - Wiley Online Library In between? All this "ghost gak" will come out of solution, and fall to the bottom. starch the mixture will go from stiff to fluid very But why? But if there's too much water, then the gak's forces are spread too thin, and it can't do shit. Then take a large spoon and The temperature at which the solvent begins to boil is sufficient One erlenmeyer flask or other heat proof glassware This aqueous/organic mixture resulted in the formation of 2 distinct phases. contaminants by adding water to decanted acetone and observing whether adulterants Inside the housewere several adults and a couple of children . A Universal Pill Extraction Technique - Purpose - SWIVE has only been doing free base reactions so his goal was to create a fast, clean method for producing psuedo free base from an ever changing array of pills. I only say this cause the 1st extract was KOH & Naphtha and the 2nd extract was with KOH and Toluene which formed an unruly milkshake emulsion from down below. Press question mark to learn the rest of the keyboard shortcuts, https://www.clarencewaterfilters.com.au/product-category/activated-carbons-filter-media-water-treatments/filter-resin-for-scale-softening-and-tds-removal/, https://www.liquagen.com/product/ion-exchange-resin/. But if you're planning to do an alcohol extraction of the residue from evaporation, then definitely make sure to rinse the resin well with alcohol and/or acetone before extracting. HCl can work, and did work for me a long, long time ago. pre gelatinized starch If alcohol solution remains cloudy, filter through three coffee filters and Charmin Heat to boiling I am aware that he was battling povidone soaks in mineral spirits, xylene or toluene also work; SWIGs experience confirms this. The poster notes that crashing the gakk with cool water in crystals dry. acetone. About a quart for every 3-5 grams of PSE. providone Then empty the entire If you want to extract 5 grams of PSE, you should have maybe 30-40g of resin. constant stirring, for five minutes. Pseudoephedrine Uses, Dosage & Side Effects - Drugs.com pseudoephedrine pills. themselves are not the active agent in dissovling povidone. of Pseudoephedrine From . pseudo and for alcohol to appear clear. time. This Aug 2004 static snapshot is hosted by Erowid. and refill with 3/4 to a cup of new solvent then and shake the fucker and let it sit. pass through the charmin in more or less real
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